Dosage ranges shown are based on published research and are for educational reference only. Your protocol reflects these based on your intake assessment. Always consult your healthcare provider before starting any supplement.
SUPPLEMENTS
The Biolune Protocol Stack
14 research-informed supplements from 7 world-leading health experts. Not random pills. A structured protocol, informed by peer-reviewed research and your data.
HOW IT WORKS
Your Stack, Your Data
Apply Now
Tell us about your goals, lifestyle, diet, and health history. Takes 3 minutes.
Research Matching
Your profile is compared against published protocols from Huberman, Attia, Patrick, Walker, Sinclair, Brecka, and Johnson. The system shows what aligns with your goals, your intake data, and your budget.
Get Your Stack
A morning and evening stack informed by your data. What to take, what to skip, and why. Every supplement tells you why it's in your stack.
TIER 1 — UNIVERSAL
Foundation Stack
The essentials every protocol starts with — backed by all 7 experts.
Vitamin D3 + K2
Most people are deficient and don't know it. D3 covers the gap. K2 makes sure the calcium goes to your bones, not your arteries.
Omega-3 (EPA+DHA)
One of the most widely studied supplements in health research. Omega-3 is associated with support for inflammatory balance, cognitive function, and cardiovascular wellness.
Magnesium (Threonate or Glycinate)
Most adults are low in magnesium. It's involved in over 300 processes, but you'll feel the difference in sleep and recovery first.
Creatine Monohydrate
The most studied sports supplement in history. Cheap, effective, well-tolerated. Builds strength and increasingly linked to cognitive performance.
TIER 2 — GOAL-BASED
Sleep Architecture
Sleep is the single most effective performance enhancer. These support deep, restorative rest.
Magnesium L-Threonate
The only form that crosses the blood-brain barrier efficiently. If you're taking magnesium for sleep, this is the one that actually reaches your brain.
L-Theanine
Takes the edge off without making you groggy. Quiets the mind before bed. No sedation, no morning hangover.
Apigenin
A flavonoid from chamomile that Huberman credits with deeper, longer sleep. Low dose, no dependency, no tolerance buildup.
TIER 3 — ADVANCED
Cellular Wellness
Supplements studied for their role in supporting cellular energy, repair, and long-term vitality.
NMN (Nicotinamide Mononucleotide)
NAD+ levels naturally decline over time. NMN is studied for its role in supporting mitochondrial function and cellular energy production.
Sulforaphane
Research suggests sulforaphane may activate the Nrf2 pathway, which supports the body's natural antioxidant processes. Broccoli sprout extract is the most practical delivery method.
Fisetin
Fisetin is studied for its potential senolytic properties — supporting the body's natural process of clearing aged cells. Early research is promising but ongoing.
Resveratrol
Studied for its role in supporting sirtuin activity. Often paired with NMN in longevity research. Take it with a fat source for better absorption.
TIER 2 — GOAL-BASED
Performance & Vitality
Support natural vitality and energy, focus, and physical output.
Tongkat Ali (Eurycoma longifolia)
Studied for its potential to support natural balance. One of the more researched herbal adaptogens in this space.
Alpha-GPC
Pre-workout focus in a capsule. Feeds the neurotransmitter responsible for attention and mind-muscle connection.
Ashwagandha (KSM-66)
One of the most researched adaptogens, associated with supporting healthy cortisol response under stress. KSM-66 is the extract form with the strongest evidence base.
YOUR PROTOCOL
Not Sure Where to Start?
These are the protocols — but not everyone needs all of them. Lune surfaces research relevant to the supplements in your protocol — based on your data, goals, and lifestyle.
BUILT-IN AWARENESS
Awareness Before You Start
Supplements can interact with medications and conditions. The system highlights potential interactions to discuss with your doctor, based on what you share in your intake. Not a replacement for medical advice. A starting point for a smarter conversation.
Thyroid medication → shows timing conflicts to discuss with your doctor
Pregnancy / nursing → shows compounds not considered safe
Autoimmune conditions → shows immune-stimulating ingredients for review
MTHFR variant → shows alternative folate forms
Statins → shows potential CoQ10 interaction for your physician
EXTERNAL RESOURCES
For Elite subscribers (launching Q1 2027)
Test. Upload. Review.
Your protocol becomes more relevant with real data. Order a blood panel or DNA kit, upload your results, and Lune surfaces research relevant to your results.
BLOODWORK
Know your numbers
An Elite-tier blood panel covers ApoB, HbA1c, hsCRP, Vitamin D, and more. Biolune surfaces insights from 15+ wellness markers for your review.
RAW DNA
Read your genetic code
Upload your raw DNA file and Lune surfaces research relevant to genetic variants related to methylation, detox pathways, nutrient metabolism, and more.
Once you have your results, upload them in the Biolune app. Lune presents updated context within 48 hours for your review.
Expert Sources
Every reference is sourced from the published protocols of: Andrew Huberman (Stanford Neuroscience), Peter Attia (Longevity Science), Rhonda Patrick (Biomedical Science), Matthew Walker (Sleep Science), David Sinclair (Genetics, Harvard), Gary Brecka (Human Biology), and Bryan Johnson (Blueprint Protocol).